TALENs Technology for Targeted Genome Editing

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TALEs (Transcription Activator-Like Effectors) are proteins that bind to DNA in a sequence-specific way. The newly-developed transcription activator-like effectors nucleases (TALENs) comprise of a nonspecific DNA-cleaving nuclease fused to a DNA-binding domain that can be easily engineered so that TALENs can target essentially any sequence.



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